Endoplasmic Reticulum and Its Role in Tumor Immunity
by Paul Eggleton, et al.
Publisher: Frontiers Media SA 2016
Number of pages: 101
The endoplasmic reticulum (ER) is an organelle crucial to many cellular functions and processes, including the mounting of T-cell immune responses. Indeed, the ER has a well-established central role in anti-tumor immunity. Perhaps best characterized is the role of the ER in the processing of antigen peptides and the subsequent peptide assembly into MHC class I and II molecules.
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