Statistical Genetics and Evolution of Quantitative Traits
by Richard A. Neher, Boris I. Shraiman
Publisher: arXiv 2011
Number of pages: 23
This review provides a simplified exposition of the concept and mathematics of Quasi-Linkage Equilibrium (QLE) which is central to the statistical description of genotypes in sexual populations. We show how key results of Quantitative Genetics such as the generalized Fisher's Fundamental Theorem, along with Wright's Adaptive Landscape, emerge within QLE from the dynamics of the genotype distribution.
Home page url
Download or read it online for free here:
by Eric S. Lander, Michael S. Waterman - National Academies Press
Leading experts look at how mathematical methods have made possible important discoveries in biology. Explores how differential geometry, topology, and differential mechanics have allowed researchers to unwind and understand DNA's double helix.
by Eugene V. Koonin, Michael Y. Galperin - Springer
An introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. Perfect for introductory level courses in computational methods for comparative and functional genomics.
- ETC Group
This text covers synbio basics, gives an introduction to five major areas of research in synthetic biology, presents implications of synthetic biology, and gives a case study: microbial production of artemisinin to treat malaria.
by Nicholas H. Bergman - Humana Press Inc.
A collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. The available chapters describe National Center for Biotechnology Information resources available to the public.