Extreme Genetic Enginering: An Introduction to Synthetic Biology
Publisher: ETC Group 2007
Number of pages: 72
Transgenics, the kind of engineering you find in genetically modified tomatoes and corn, is old news. As recombinant DNA splicing-techniques turn 30 years old, a new generation of extreme biotech enthusiasts have moved to the next frontier in the manipulation of life: building it from scratch.
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The book covers a wide range of topics in genetic engineering of microorganisms, plants and animals: the genetic engineering of microorganisms to produce antibiotics, the gene targeting and transformation in plants, and much more.
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This review provides a simplified exposition of the concept and mathematics of Quasi-Linkage Equilibrium (QLE) which is central to the statistical description of genotypes in sexual populations. We discuss under what circumstances QLE is applicable.
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